

🐕🦺 Elevate your pet’s skin health game — because they deserve the best!
S3 Pyo Shampoo by Douxo is a veterinarian-recommended antiseptic and hydrating shampoo formulated with 3% Chlorhexidine and 0.5% Ophytrium. Designed for dogs and cats with bacterial or yeast skin infections, it soothes irritation, supports the skin barrier, and reduces yeast counts within a week. Free from harsh chemicals, this 6.7 fl. oz. liquid delivers gentle yet effective cleansing, leaving coats soft, shiny, and healthy.





| Brand | Douxo |
| Customer Reviews | 4.7 out of 5 stars 6,961 Reviews |
| Item Form | Liquid |
| Liquid Volume | 6.7 Fluid Ounces |
| Material Type Free | Paraben Free,Sulfate Free |
| Product Benefits | Soothing,Moisturizing,Detangle |
| Recommended Uses For Product | For Bacterial or Yeast Skin Infections For Dogs and Cats |
M**G
Great Product, Immediate Relief
Easy and reliable to pump shampoo out, lathered very well on thick double coat, less redness and irritation right out of the shower, pleasant smell - nothing to complain about.
T**S
Amazing Stuff - fixed my dog's skin issues!
My dog had maybe a yeast infection, skin allergies... idk. He had scabs and dandruff all over his back and belly, and lots of discoloration on his belly which came out of nowhere, He was constantly itching and I felt so bad for him ): I decided to look into it and found people with similar issues. So, with recommendations, I found this shampoo, and also switched his dog food to a better one. With the switch of his dog food, I can't say that one or the other fixed his skin, or both was the solution, but either way, his skin and coat has made a DRASTIC change in just one month. I have been washing him every 3-4 days with this shampoo for a month now, scrubbing him very well and leaving it to sit on him for 5-10 mins. He hates baths but it's what we have to do! This stuff smells great, it suds up and has a nice lather, rinses well, and leaves his coat feeling soft and clean! I can't complain at all. Yes it is pricey as heck, but if it works how can I complain. when I was researching on the internet for my dog's specific issues, I saw people with similar issues say their dog had a yeast infection, and when they took their dog to the vet, this is what their vet recommended! This is what made me take the jump on the purchase and I was not disappointed.
H**R
5 Stars - HIGHLY Recommend! Works Amazing for Allergies!
Hands down the best dog shampoo I've ever used.y American Pitbull is allergic to everything,I even had him undergo the prick test with the Dermatologist & he's allergic to 40 out of 46 items tested for. So his skin is always broken out, even while doing the Allergy Immunotherapy injections, I'm averaging every 3rd day on giving him another bath & this shampoo is helping him so much! He will be completely broken out, red bumps & hives all over his body, I'll give him a bath & within a few hours, or by the next morning (since I usually bathe right before bed) his skin has significantly improved, half the bumps will be gone, most of the hives are completely gone & the redness is nonexistent! The smell is really great as well, it's a lighter scent, I don't smell any chemicals or any of the normal medicated smell at all & it's light enough you can smell it on your pup if you're up close, but otherwise it's not noticeable. The formula is decently thick, it's not runny at all, but it suds up so great as well - another huge thing most medicated shampoos don't do! You also only need a small amount, it actually advises how much to use on the bottle depending on how large your dog is, but it's so easy to suds up, that you don't need much at all. I have a 64lbs Pitbull & I only use 2 pumps on his whole back, 1 on each side & 1 pump on each leg & that's about it. So the cost is a bit expensive, but it lasts forever with how little you need & with how well it works, its 100% worth it. The pump works great, it has the locking mechanism when you turn the pump to the side, so you don't have to worry about it leaking, we transport it every weekend to our MIL's house, and I just throw it in the bag, never leaked before, you don't have to worry about it. I can't recommend this shampoo enough or stress how well its been working for our 4 dogs!
T**S
Every dog is different.
With a pitty with severe allergies (white) her breakouts can get out of control. I have found that bathing her with this shampoo only once a week has done wonders - of course, in addition to her Prednisone every other day.... I recommend this shampoo for help with breakouts, itching, and redness. (I also use Rosemary oil for her paws/scarred areas after her bath) Please note that I have been living with a white Pitty whos vet, food, and special items adds up to about $1,000.00 extra a year (in addition to regular doggie costs) but I will also say - not ALL dogs will react to a product the same way another one does. It will Always be trial and error with allergies and pets. Just like adults - ya gotta find what works for them :) Good luck!
A**.
Works wonders for Skin yeast!
My lab stunk!!! And itched non stop. This shampoo is an absolute lifesaver. The yeasty smell is gone and her skin is so much better and hair is growing back. I did so much research looking for a magic pill and that wasn’t the problem. It was her skin. I now bath her underbody 1x a week to keep her skin healthy. This was recommended by a vet.
S**S
Small bottle but works
I have a shihzu mix and with the weather changing she has been licking and scratching a lot. So she developed fungus on her stomach and paws. I decided to look for shampoo to treat it and since I work with dogs this was a safe smart choice. I did what the instructions said and left it mainly on her stomach and paws for 5-10 minutes. It only has been a few days and her stomach has healed drastically. It’s not 100% better but it says to use 2 times a week. The smell is very light and not overpowering which I like and can be layered. But I would layer it with anything that can’t cause more irritation so a light sensitive condition for allergies would be best after this product. For the price of the bottle is ok, I wish it was a little bigger but for it to be an over the counter medicated shampoo and works, anything for my baby. But it’s not an everyday shampoo, use the bottle as needed and if gets worse then see a vet. Not all products works for every animal, if having doubt confirm with vet but for myself I woulds say the product works
S**M
Worth EVERY Penny
This shampoo has been an absolute game-changer for my dog. She’s 13 years old now and has struggled with itching her entire life. We’ve tried just about everything over the years—multiple prescriptions, countless vet-recommended products, and so many over-the-counter solutions. Nothing ever gave her real relief until we started using this shampoo along with the mousse. The difference has been incredible. She used to spend her days constantly scratching and licking, and nights were often the worst—waking up itching, sometimes even crying out in discomfort. It was heartbreaking to watch. Since switching to this product she’s finally comfortable. She sleeps peacefully through the night now, complete with the sweetest little snores, and during the day she’s relaxed instead of restless. It’s been amazing to see her quality of life improve so dramatically. I’ve been using this consistently for months and I’m a repeat purchaser—I’ll never be without it. It not only calms her skin but also keeps her coat soft, clean, and so fresh smelling. I did find that buying directly from the company offers a better price, but regardless, this shampoo (and mousse) are worth every penny. If you have a dog struggling with chronic itching or irritated skin, I can’t recommend this product enough. It has truly been the only thing that has worked for us after years of searching, and it’s given my dog the comfort she deserves.
B**R
Works well!!
This is a great shampoo for my maltipoo. It smells nice and decreases his itchiness.
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