Super Agers: An Evidence-Based Approach to Longevity

I have read all of Dr. Topol's books and this one is no exception. There is a lot of up to date information about studies relating to aging and the disease. The book does an excellent job of summarizing a vast array of technological tools that can be used for diagnosing or potentially treating diseases or conditions that can accelerate aging. If someone has put something out in a study, then likely you will read about it in this book. The book is a great reference and although you will understand it better with a science background, if you are willing to take the time to process the information or look at the graphs and diagrams, then you can at least have an awareness that you would not have had before getting the book. It is not a page turner from a storytelling perspective but it is in terms of all of the new and unique angles that are covered in this book that are's covered even in Dr. Attia's book Outlive or in Dr. Greger's book How Not to Age. Overall an informative and enjoyable read!

Great information about diet and how to stay healthy

Overall, Dr. Topol’s book offers a valuable overview of the medical literature relevant to aging. However, as a psychiatrist, I found Chapter 11, which addresses mental health, lacking in several important respects. First, Dr. Topol’s discussion of SSRIs in major depressive disorder (MDD) is incomplete. While he notes that the effect size of SSRIs is modest in depression, he omits the robust evidence supporting their efficacy in cases of severe major depressive disorder. Multiple meta-analyses and clinical guidelines indicate that SSRIs are effective for moderate to severe depression, particularly when combined with cognitive behavioral therapy. The effect size may be small in mild depression, but for severe cases, SSRIs remain a cornerstone of treatment and are recommended by major guidelines. Additionally, SSRIs are effective in preventing relapse when continued as maintenance therapy. Second, the chapter raises unwarranted doubts about the effectiveness of electroconvulsive therapy (ECT) for depression. On page 270, Dr. Topol questions whether ECT is a valid treatment for depression. This overlooks a substantial body of evidence demonstrating that ECT is highly effective for treatment-resistant depression, bipolar depression, and certain cases of refractory psychosis, such as catatonia. While ECT is not appropriate for all patients, it is a critical option in the therapeutic armamentarium for select, severe cases. In summary, while Topol’s book is generally informative, the treatment of psychiatric interventions—especially regarding SSRIs and ECT—does not fully reflect the strength of the current scientific evidence. A more nuanced and comprehensive discussion would have better served readers seeking guidance on mental health in the context of aging.

Love this book! Dr. Topol covers the gamut of longevity in health research. Pragmatic view of the role of obesity, exercise, and diet in life extension. I appreciated the chapters where he points out scant empirical data supporting a health goal. For instance, the 10,000 steps per day widely in use does not have metadata supporting health. May be as few as a daily goal of 2,700 steps. The USA has one of the least healthy populations. From highly processed food to sedentary lives we have a serious crisis at play. The 2013 classification of Obesity as a disease is a start. Super Agers fills in the blanks on how to resolve this issue.

Why not explain the numerous graphs? This is a detailed description of many research findings related to healthy aging. I like the way the author does not water down the science, but even though I am a scientist, I have no idea what information most of the graphs show. The author does not define axes or abbreviations. If one of my students handed in a paper with such terrible graphs, they would get a C, even in this age of grade inflation. The writing is mostly clear, but could use more informative summaries at the end of paragraphs and sections.

No-nonsense, clear, and authoritative advice for increasing your health span.

This is one of the best books that explains the current state of evidence based medical research in the areas of chronic illness and its impact on healthy aging and increasing one’s health-span. With the advent of new medical discoveries and technologies Dr. Topol makes a strong case for converting our current health system from one of reactive prescription to early identification and prevention. A great read if you want to understand the current state of medical research and its future impact on aging. Dr. Topol provides an honest assessment of the current and future state of medical research by debunking many misinformed myths and provides an optimistic path for the way forward to better health and a longer life. A highly recommended read from a real cardiologist.

Rather technical. Good information, but not the easiest read.

Great book that puts everything into perspective that is evidence-based. A good side book to Dr.Greger's How NOt to Age. Everyone caught up in tiktok, instagram and "biohackers" who are NOT researchers should read this book as here's where the actual outcomes of studies is weighed properly. There are so many easy-to-read sections that will ease your mind and help your lifestyle. I use these two books in my personal training, cancer exercise, osteo fitness classes. All of the info. is so approachable and written in a way that will sit comfortably with any member of your family you hope to help. I loved his interviews with MelRobbins, Diary of a CEO which complemented the information in Superagers.

Aun con el ocasional humor norteamericano, es un libro que habla de investigaciones serias sobre el mejor envejecimiento fisiológico: morir joven lo más tarde que sea posible Una inversión redituable!

Science based

Es una perfecta revisión bibliográfica de la medicina que podemos aplicar a día de hoy y espero que se pueda difundir esta forma de aplicar y practicar la medicina de una forma generalizada en un futuro próximo.

Interestingly, however, the same information is repeated throughout the book.