ALCOHOL RESISTANT Markers, FINE POINT, Designed for Industrial, Laboratory & Hospital Use, 3 per Pack: 1 Red & 2 Black

Discovered these markers on r/labrats after getting frustrated with labels wiping off in tissue culture from vwr cryo markers. These are the bomb.Look, if you need to write on surfaces stored at cryo to physiological temperatures where if the writing came off, you’d be screwed or compromise cell line identification or sample identity, these are your markers. Yes, they are expensive. They are expensive because they are excellent at what they are designed to do. The cost of misidentifying precious samples significantly outweighs the cost of the pen.Pros:- Works excellently at -196, -80, -20, 4, 25, 37 C. Can still see writing through frost which is nice when searching for vials quickly. Doesn’t wipe off easily at the extreme low temperatures like typical cryomarkers or sharpie ultra fine, but may still get some slight shedding. Shedding usually only happens when I haven’t wiped the marker in a while and a thicker layer of ink is dispensed while writing.- Writing survives after being completely submerged in pure bleach or 200 proof ethanol over several days after testing.- Has lasted several months of daily heavy use without fading like the typical Sharpie ultra fine point. Always writes with a bold black.Cons:- It takes some getting used to waiting for them to dry, but unconsciously you get used to it. I am right handed so not as much of an issue. For those that are left handed, I’m sure you’ll have to elevate the edge of you hand so you don’t smear the writing as it dries. This is no different than when you’re regularly labeling Eppendorf tubes.- If you smear it on something e.g. deck of a tissue culture hood, you MUST spray it down with 70% ethanol very quickly and start scrubbing with ethanol to get it off before fully drying. Otherwise you’ll just have to work it off with physical force over time.- Tip can come out easily if you accidentally push too hard or wipe the tip fast. Being gentle helps here. Pen will start dispensing a lot of ink but if you just put the tip back in, wipe it, and store it as suggested, it goes back to normal.- Sometimes dispenses too much ink if not wiped in a while. This can be frustrating when labeling vials quickly in a laminar flow good because the air flow will make the ink run while drying. You learn how to adapt your writing style to fix this. For Eppendorf tubes with the frosted writing area, because the ink is “heavier” (think more of an oil-based ink rather than alcohol based sharpie permanent marker) it likes to spread out more as it dries because of the surface is actually gritted.- Doesn’t always like to adhere to specific surfaces unless you’ve freshly re-primed the marker and write slower. I find that this happens on things that have special chemical resistance coatings e.g. Fisherbrand labeling tape (waterproof, oil & acid resistant).Buyer Notes:- The red/pink marker writes in a pink color. Thought it was going to be red.- Think of this marker as writing in a bolder font when compared to an ultra fine point Sharpie permanent marker but finer than a Sharpie fine point. You may find that you cannot write as many things on say a 1.7 mL Eppendorf tube cap compared to an ultra fine point marker. You trade ultra fine writing for a writing point between ultra fine and fine sharpie permanent marker that is bold and ultra permanent.These markers were so good that my adviser adopted them for our tissue culture facility. I love them and think you will too. There’s no going back after having these.

I've been searching for a completely isopropyl proof marker to use for years, and this is exactly what I wanted!! It does not fade at all when I douse it in 70% isopropyl!! The writing is very dark and much more visible than the vwr or fisher lab markers. I have used it for about a week and have not had problems with it drying out/not writing.See my photo:The first tube "test" was allowed to dry for less than one minute, then heavily sprayed with 70% isopropyl and scrubbed with a paper towel. The second tube "test 2" was allowed to dry for 1-5 min then sprayed with isopropyl and scrubbed. I also tried scraping the ink off with a fingernail and only did minor damage to the "3" in the date.Pros:-Completely resistant to isopropyl alcohol after about a minute-Ink is completely opaque-this is the only fine-tip xylene marker I have ever found-difficult to scratch offCons:-Ink does not dry instantly and may bleed-I wish it wrote a little finer-I think it could dry or get clogged if you leave it uncapped in a biosafety cabinet or fume hood.

Yes, the liquid inside these pens works well and does resist alcohol. But the containers leak often/most of the time. The cap is tight and after removing several times, the front end of the pen starts to disconnect from the back end which contains the ink. Not only is lots of ink wasted. But then the ink ends up on your hands...and other places. And it is, indeed, hard to remove from those places. I have bought these pens several times. But at $30 the set the makers should (and can afford) to design a better delivery system.

Markings I put on glass beakers have lasted through over 30 wash cycles so far. I didn't waste my money on this one.

They might be a little expensive for 3 markers, but they are fantastic. They are like a paint pen that actually works every time, but still have the fine tip of a small marker. I carry one of these with me to mark anything you can imagine from glass plates, to metal, to even porous materials like wood. I’m extremely impressed and will definitely buy these again!

This is by far the best ink on the market. I did a test run using multiple "permanent inks" against multiple cleaning solutions, and this is the only ink that lasted. (it did smudge a little). The problem lies with the valve marker design. It seems like the ink dries into the fine tip after one use and clogs up the tip. After one use the only way to get out the ink is to over-prime it and let the ink form a large puddle on a piece of scratch paper and constantly dip the tip of the marker into the puddle to write. This marker definitely has potential but the valve tip needs a redesign as it turns a $40 marker into trash pretty quick. I will be on the look out for future developments!

Good

These markers are alcohol resistant. They take a few seconds to dry but once dry it will not rub off with alcohol.Markers are very expensive, but it lasts much longer than VWR or fisherbrand felt tip lab markers.The ink tends to write a bit thicker so it is difficult to write on PCR tubes.Very good for lab work where IPA is used regularly.